A Case of Pneumatosis Cytoides Intestinalis Successfully Treated by Inhalation of High Concentration Oxygen

A 44-year-old man was referred to our hospital because of a positive fecal occult blood test. A barium enema study revealed numerous oval-shaped, elevated lesions with smooth surfaces in the region including the ascending colon. He was admitted to our hospital for investigation and therapy. Based on colonoscopic examination, we diagnosed him as having pneumatosis cytoides intestinalis (PCI). He was treated with oxygen (5L/min5 hours/ day for 14 days) via a nasal cannula. Most of the multiple cysts diminished and some changed into white scars. The simplicity of oxygen therapy supports its use as a first-line treatment.