Eine neue synthese von vinblastin-derivaten v. konzept und untersuchungen zur synthese von 20'-desethyl-20'-desoxy- c'-homovinblastin—octahydro-3H-azecino[5,4-b]inidol-derivate
1990
Zusammenfassung A concept for the synthesis of C'- homovinblastine derivative 1 is presented in which the azecinoindole derivative 3 and the bicyclic lactam 5 are key intermediates. Starting from tryptamine, the synthesis of these two intermediates is described. In addition, the C-homocleavamine derivative 14 is synthesized.
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