Preparation and Properties of Pesticide-loaded Carboxymethyl Chitosan Microsphere

Controlled release system has been widely developed and used in agriculture to improve efficacy and minimize environmental pollution. Here, the pesticide-loaded carboxymethyl chitosan microspheres were constructed by suspension-crosslinking method. Carboxymethyl chitosan was used as a carrier to formulate microsphere to load neonicotinoids with a mixture of calcium chloride and glutaraldehyde as double-component cross-linking agent. The resulting microsphere processed high drug loading and encapsulation efficiency with a mean diameter of 1 mm. The UV detection method of pesticide was established, which was convenient and quick. The pesticides release properties of the microspheres were investigated, and the controlled release time was more than 6 days, which achieves the objective of improving the efficacy of the pesticides. This work would promote the development of controlled-release pesticide systems.