INSIGHT INTO THE ROLE OF SERUM MAGNESIUM IN GLYCEMIC CONTROL OF TYPE 2 DIABETES MELLITUS

Background: Intracellular magnesium (Mg2+), a macro mineral plays a key role in regulating insulin action. Thus magnesium deficiency can contribute to insulin resistance. In this regard we have studied the serum magnesium levels to know its relationship with type 2 diabetes mellitus (type 2 DM) and also to evaluate its association with the glycemic control. Materials and Methods: One hundred and fifty subjects in the age group of 35-60 years attending medical OPD of Rajarajeswari Medical College and Hospital, Bengaluru, were included in the study. Hundred, type 2 DM patients were divided into two groups; group I -consisting of fifty subjects with poor glycemic control and group II- fifty subjects with good glycemic control. Fifty, non-diabetic apparently healthy volunteers were considered as group III. Serum FBS and PPBS was estimated by GOD-POD method, Glycosylated Hemoglobin (HbA1c) by particle enhanced immunoturbidimetric method and Serum Magnesium by Xylidil blue spectrophotometric method. Results:…