Knowledge Graphs in the Quality Use of Antidepressants: A Perspective from Clinical Research Applications

The incidence of depression has increased dramatically in recent years and the quality use of antidepressants has drawn extensive concerns worldwide. In this paper, firstly, we analyze current barriers regarding the use of antidepressants. Secondly, a new informative system which is developed using knowledge techniques is proposed, and its role in the management of antidepressants is discussed. Three main functions of the current version of Knowledge Graphs for Depression (DepressionKG, version 0.6) are presented. Besides, we conduct a semi-structured focus group interview to evaluate this system. The results indicate that DepressionKG has the potential to be a feasible, evidence-based tool for healthcare professionals.