Cancer Mortality In The British Rubber Industry – A 45 Year Follow-Up: Progress Update To Spring 2015

Objectives Working in the rubber and rubber product manufacturing industry has been classified by the International Agency for Research on Cancer (IARC) as definitely carcinogenic. However, given the complex nature of the chemicals, the phasing out of the use of certain chemicals, and the trend in reduction in exposures, there remains a great deal of uncertainty about the nature of the risks, if any, encountered by workers today. Method We have at our disposal a large retrospective cohort study of over 40,000 workers who were aged 35 and over in 1967, which was last followed up to 1976. We are carrying out an updated cancer mortality analysis and we hope to additionally study cancer incidence. We will determine the nature of the dose-response relationships for the most important known and suspected carcinogens using available data in the EXASRUB database. Results We will report on progress to date with the study, which has received ethical approval and is currently seeking other clearances from the UK res...