Novel 1,3-Dipolar Cycloaddition of Diazocarbonyl Compounds to Alkynes Catalyzed by InCl3 in Water.

The first intermolecular 1,3-dipolar cycloaddition of diazocarbonyl compounds with alkynes was developed by using an InCl3 catalyzed cycloaddition in water. The reaction was found to proceed by a domino 1,3-dipolar cycloaddition–hydrogen (alkyl or aryl) migration.