A Three-Component Reaction of Phenol, Aldehyde, and Active Methylene Substrate under Lewis Acid Catalysis: Successful Trapping of o-Quinone Methide to Afford Benzopyran Systems.

Sabir H. Mashraqui,Mamta B. Patil,Hitesh D. Mistry,Shailesh G. Ghadigaonkar,Auke Meetsma

A Three-Component Reaction of Phenol, Aldehyde, and Active Methylene Substrate under Lewis Acid Catalysis: Successful Trapping of o-Quinone Methide to Afford Benzopyran Systems.

2005

Sabir H. Mashraqui
Mamta B. Patil
Hitesh D. Mistry
Shailesh G. Ghadigaonkar
Auke Meetsma

A three-component condensation involving reactive phenols, aldehydes, and active methylene substrates is described under BF3.Et2O catalysis to afford benzopyranyl products in satisfactory yields.

Keywords:

Aldehyde
Phenol
Quinone methide
Methylene
Trapping
Lewis acid catalysis
Substrate (chemistry)
Benzopyran
Chemistry
Organic chemistry
o quinones

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