The treatment of advanced bladder cancer with sensitized pig lymphocytes

Twenty-five patients with transitional cell carcinoma of the urinary bladder have been treated by infusion of sensitized pig lymph node cells into the arterial blood supply of the tumour. In 7 cases pig cell infusion was the only treatment, in a further 7 patients pig cells were given in the treatment of a major tumour recurrence following radiotherapy and in 11 patients pig cell infusion was followed after 4-8 weeks by an attenuated course of radiotherapy. In these three treatment groups 2, 3 and 9 patients respectively obtained clinical benefit and biopsy showed histological change.