A phase II study of topotecan and cisplatin with sequential thoracic radiotherapy in elderly patients with small-cell lung cancer: Okayama Lung Cancer Study Group 0102

Toshio Kubo,Keiichi Fujiwara,Katsuyuki Hotta,Toshiaki Okada,Shoichi Kuyama,Shingo Harita,Takashi Ninomiya,Haruhito Kamei,Shinobu Hosokawa,Akihiro Bessho,Tadashi Maeda,Toshiyuki Kozuki,Nobukazu Fujimoto,Kiichiro Ninomiya,Mitsuhiro Takemoto,Susumu Kanazawa,Nagio Takigawa,Masahiro Tabata,Mitsune Tanimoto,Hiroshi Ueoka,Katsuyuki Kiura

A phase II study of topotecan and cisplatin with sequential thoracic radiotherapy in elderly patients with small-cell lung cancer: Okayama Lung Cancer Study Group 0102

2016

Purpose The treatment outcome in elderly patients with limited-disease small-cell lung cancer (LD-SCLC) remains poor. We carried out a phase II trial of split topotecan and cisplatin (TP) therapy and sequential thoracic radiotherapy for elderly LD-SCLC patients as a follow-up to our previous phase I trial.

Keywords:

Cisplatin
Phases of clinical research
Topotecan
Intensive care medicine
Radiation therapy
Chemotherapy
Pharmacology
Lung cancer
General surgery
Medicine
thoracic radiotherapy
non small cell
Oncology
treatment outcome
Internal medicine

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