Abstract 16167: A GWAS of EHR-Defined CAD Identifies Multiple Novel Loci Including the First 3 Loci on the X-Chromosome: The Million Veteran Program

Themistocles L. Assimes,Scott M. Damrauer,Jin Li,Yan V. Sun,Julie Lynch,Derek Klarin,Scott L. DuVall,Jie Huang,Jason L. Vassy,Jennifer Lee,Matthew S. Freiberg,Deepak Voora,Sekar Kathiresan,William E. Boden,Pradeep Natarajan,Donald R. Miller,J.M. Gaziano,John Concato,Kelly Cho,Peter W.F. Wilson,Daniel J. Rader,Philip S. Tsao,Christopher J. ODonnell

Abstract 16167: A GWAS of EHR-Defined CAD Identifies Multiple Novel Loci Including the First 3 Loci on the X-Chromosome: The Million Veteran Program

2017

Introduction: Genome wide association studies (GWAS) to date have identified 78 susceptibility loci for coronary artery disease (CAD). These loci explain a modest fraction of the heritability of CA...

Keywords:

X chromosome
Heritability
CAD
Medicine
Genome-wide association study
Genetics
susceptibility locus
Locus (genetics)
Coronary artery disease

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