Case report of osmotic demyelination syndrome in two patients with hypopituitarism during treatment and literature review

Patients with hypopituitarism often develop chronic hyponatremia,and osmotic demyelination syndrome(ODS) is seldom happened during the treatment.Two cases with hypopituitarism occurred ODS were reported here and the reasons were analyzed.Overly rapid correction of chronic hyponatremia can lead to ODS.The prevention of ODS is the key.Currently,there is not special treatment,and combining treatment is needed. Key words: Osmotic demyelination syndrome;  Hypopituitarism;  Hyponatremia