Accidents vasculaires cérébraux des drépanocytaires : apport du Doppler transcrânien et de l'imagerie en résonance magnétique Stroke in sickle cell disease patients: transcranial Doppler and magnetic resonance imaging

Sickle cell disease (SCD) is the most frequent cause of stroke occurrence during infancy and strokes are the most serious complication of SCD in children. Distal vasculopathy related to sludge explains 25% of strokes in SCD whereas proximal vasculopathy is responsible for 75% of strokes. The stenoses observed in this proximal vasculopathy are progressive and can be detected by transcranial Doppler (TCD), a reliable, non-invasive and low-cost methodology. High