microwave ablation therapy of giant cell tumors of bone

1. Abstracts 1.1. Aim:  Recurrence of giant cell tumor of bone was a hot topic, and the best treatment remains controversial. We tried using Microwave Ablation (MWA) to further reduce the recurrent rate. 1.2. Materials and Methods:  From May 1992 to December 2015, 233 cases of GCTs of bone were treated by MWA and 28 cases of sacral GCTs were treated by curettage plus regional chemotherapy. The procedure involved dissection of the tumor-bearing bone from the surrounding normal tissues. Antennas were inserted into the tumor cavity. The aim was to ensure that the temperature at any part of the tumor reached 80 ° C or higher and maintained for 20-30 minutes. Then, traditional curettage and reconstruction was takened. 1.3. Results:  Survival rate: 98.5%.  For 199 patients with long tube bones GCT (including 18 cases transferred from other hospitals due to recurrence), three patients who are firstly operated received revision operations for recurrence; (3/181=1.65%) two patients who are transferred to our hospital due to recurrence received secondary revision operations for recurrence. (2/18=11.1%)  For 34 patients with pelvis GCT, recurrence occurred in three cases: one patient received revision surgery without later recurrence, while two patients received an amputation. (3/34=8.8%) For sacrum, all cases achieved local control, but 4 cases received revision surgery 2 or 3 times. (4/28=14.2%) The final local control rate was 99.2% (259/261). Two patients had plate breakage. Two patients had mild infections. 1.4. Conclusions:  Microwave ablation is a reliable, effective technique to deal with GCT of bone. 2. Keywords:  Ablation; GCT of Bone; Microwave