Oksipital kemik yerleşimli langerhans hücreli histiyositoz: Olgu sunumu

Ozet Langerhans Hucreli Histiyositozis ayni histopatolojiye sahip fakat farkli klinik semptomlara neden olan hastaliklar grubu olarak adlandirilmaktadir. Uc ayri formu olan hastaligin lokalize formu Eozinofilik granulom olarak isimlendirilmektedir. Eosinofilik granulom, Langerhans Hucreli Histiyositozis grubu icerisinde klinik seyri en az siddetli ve lokalize form olup en iyi prognoza sahip alt tiptir. Tedavi secenekleri arasinda, cerrahi eksizyon, kemoterapi, radyoterapi tek basina kullanilabilecegi gibi kombine kullanimlari da bulunmaktadir. Burada, sag oksipital bolgede sislik ve agri sikayeti ile klinigimize basvuran, radyolojik tetkikleri ve histopatolojik incelemesi sonucunda Langerhans Hucreli Histiyositozis (Eosinifilik granulom) tanisi alan genc eriskin bir hasta sunuldu. Anahtar sozcukler: Langerhans hucreli histiyositozis, eozinofilik granulom, soliter kemik lezyonu Abstract Langerhans Cell Histiocytosis is termed as a group of diseases that leads to have same histopathology, but different clinical symptoms. The disease has 3 distinct forms named as fulminant (Letterer-Siwe disease), chronic recurrent (Hand-Schuller-Christian disease) and localized (Eosinophilic granuloma). Eosinophilic granuloma is typically found in children and is characterized with one or more lytic bone lesions.  Eosinophilic granuloma is the localized form of which has the least clinical severity and the most favourable subtype in Langerhans Cell Histiocytosis group. The treatment options are available as surgery removal, chemotherapy, and radiotherapy alone or in combinations. In this paper, a young adult patient was represented who referred to our clinic with complaints of swelling and pain on right occipital region, and who diagnosed as Langerhans Cell Histiocytosis (Eosinophilic granuloma) after evaluation of radiologic tests and histopathologic survey.  Keywords: Langerhans’ Cell Histiocytosis, Eosinophilic granuloma, solitary bone lesion