[Effect of moxibustion on motility, absorption and content of ATP in small intestine of spleen-deficiency rats].

2012 
Objective To explore the mechanism of reinforcing function of moxibustion to spleen-stomach.Methods Forty healthy Sprague Dawley rats were randomly divided into 4 groups: group A(blank group),group B(model group),group C(moxibustion group) and group D(herbs group).The rat model of spleen-deficiency was established by intragastric administration with 200% Dahuang(Rhubarb) infusion.The rats in group A and B,and D served as the blank control,model,and Sijunzi decoction group respectively,while those in group C received moxibustion at "Zusanli"(ST 36),"Zhongwan"(CV 12),"Guanyuan"(CV 4),"Pishu"(BL 20) and "Weishu"(BL 21),etc.The common symptoms and intestinal propulsive rate were observed.The content of D-xylose in serum was detected by phloroglucinol method.Colorimetry method was used to detected content of ATP in jejunum tissues.Results Compared with group A,the symptom score in group B was increased significantly(both P0.01),while the intestinal propulsive rates,the content of D-xylose in serum and ATP in jejunum tissues were decreased significantly(P0.05,P0.01).Compared with group B,the symptom score in group C and D was decreased significantly(both P0.01),while the intestinal propulsive rates,the content of D-xylose in serum and ATP in jejunum tissues were increased significantly(P0.05,P0.01).There were no significant difference between group C and D(P0.05).Conclusion Moxibustion at "Zusanli"(ST 36) etc.could relieve symptoms of spleen-deficiency,enhance motility and absorption functions of small intestine and improve metabolism of small intestine.The efficacy is equal to administration of Sijunzi decoction.
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