Pseudouridine and uric acid excretion in patients with viral hepatitis

: Daily excretion of pseudouridine and uric acid with urine was studied in healthy persons and in patients with viral hepatitis during various periods of the disease. Excretion of pseudouridine was increased 2.5-fold and of uric acid--2-fold within the acute period of the disease. The degree of impairment in nucleic acids metabolism could be estimated by measuring of excretion of pseudouridine and uric acid and by calculation of their ratio during various periods of the disease.