Method and apparatus for parallel analysis of organic molecules

2002 
The invention relates to a method and apparatus for parallel separating a plurality of individual samples (29) within a three-dimensional separation medium (6), wherein the following steps are carried out: DOLLAR A In a first space (2), of substantially all extends three space coordinates, the separation medium (6) is contained. A plurality of individual samples (29) is arranged in the vicinity of an interface of the first space (2), the individual samples (29) are arranged in area substantially, ie their respective focus positions are described by two coordinates. Under the influence of one or more physical quantities, the individual samples (29) are able to migrate substantially perpendicular to the surface of their application through the separation medium (6), where they are separated according to one or more of its properties. As physical quantities come as electrical forces (electrophoresis), gravity, diffusion, pressure and concentration gradients and osmosis of centrifugal forces into consideration. The detection of the individual samples (29) is carried out in selected areas (8) inside or outside of the separation medium (6) during their migration (online detection). As an alternative to on-line detection can be performed a 3-D data acquisition upon completion of the migration. To give a 3-D imaging method can be used. In the simplest case, the ...
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