Endostar enhances anti-tumor effects of radiation via inhibition of HIF-1α and bFGF in lung adenocarcinoma cell line A549

Huilin Xu,Wei Ge,Fangfang Jie,Dedong Cao,Pingpo Ming,Wei Luo,Jing Song,Changhu Li

Endostar enhances anti-tumor effects of radiation via inhibition of HIF-1α and bFGF in lung adenocarcinoma cell line A549

2013

Huilin Xu
Wei Ge
Fangfang Jie
Dedong Cao
Pingpo Ming
Wei Luo
Jing Song
Changhu Li

Objective The aim of the study was to investigate whether enhanced anti-tumor effects of endostar (ES) on radiation involved hypoxia inducible factor-1α (HIF-1α) and basic fibroblast growth factor (bFGF).

Keywords:

Lung cancer
Radiation
Lung
Basic fibroblast growth factor
Immunology
Adenocarcinoma
Cell culture
Medicine
Cancer research
adenocarcinoma cell
antitumor activity
Hypoxia (medical)
Pathology
Surgical oncology

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