Amphiphilic Polymeric Nanoparticles Modified with a Retro-Enantio Peptide Shuttle Target the Brain of Mice

Alexandra Bukchin,Macarena Sánchez-Navarro,Adam Carrera,Meritxell Teixidó,Angel M. Carcaboso,Ernest Giralt,Alejandro Sosnik

Amphiphilic Polymeric Nanoparticles Modified with a Retro-Enantio Peptide Shuttle Target the Brain of Mice

2020

Alexandra Bukchin
Macarena Sánchez-Navarro
Adam Carrera
Meritxell Teixidó
Angel M. Carcaboso
Ernest Giralt
Alejandro Sosnik

The blood-brain barrier (BBB) is a challenge for the treatment of diseases of the central nervous system (CNS) from the systemic circulation. The design of novel strategies to increase drug bioavai...

Keywords:

polymeric nanoparticles
Chemistry
Central nervous system
Systemic circulation
imaging flow cytometry
Amphiphile
Light sheet fluorescence microscopy
Peptide
Drug
Biophysics

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