Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.

Sergio Modafferi,Xiali Zhong,Andre Kleensang,Yohei Murata,Francesca Fagiani,David Pamies,Helena T. Hogberg,Vittorio Calabrese,Herbert M. Lachman,Thomas Hartung,Lena Smirnova

Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.

2021

Sergio Modafferi
Xiali Zhong
Andre Kleensang
Yohei Murata
Francesca Fagiani
David Pamies
Helena T. Hogberg
Vittorio Calabrese
Herbert M. Lachman
Thomas Hartung
Lena Smirnova

Background: Autism spectrum disorder (ASD) is a major public health concern caused by complex genetic and environmental components. Mechanisms of gene–environment (G×E) interactions and reliable bi...

Keywords:

Biology
developmental neurotoxicity
Autism spectrum disorder
Gene
Public health
Genetics
Chlorpyrifos

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