Long-term and ‘patient-reported’ outcomes of total esophagogastric dissociation versus laparoscopic fundoplication for gastroesophageal reflux disease in the severely neurodisabled child
2015
Abstract Aim Fundoplication has high failure rates in neurodisability: esophagogastric dissociation (TOGD) has been proposed as an alternative. This study aimed to compare the long-term and ‘patient-reported' outcomes of TOGD and laparoscopic fundoplication (LapFundo). Methods Matched cohort comparison comprises (i) retrospective analysis from a prospective database and (ii) carer questionnaire survey of symptoms and quality of life (CP-QoL-Child). Children were included if they had severe neurodisability (Gross Motor Function Classification System five) and spasticity. Results Groups were similar in terms of previous surgery and comorbidities. The TOGD group was younger (22 vs. 31.5months, p =0.038) with more females (18/23 vs. 11/24, p =0.036). TOGD was more likely to require intensive care: operative time, length of stay and time to full feeds were all longer ( p p =0.34) and use of acid-reducing medication (13/24 vs. 4/23, p =0.035) were higher for LapFundo. Carer-reported symptoms and QoL were similar. Conclusions TOGD had similar efficacy to LapFundo (with suggestion of lower failure), with comparable morbidity and carer-reported outcomes. However, TOGD was more ‘invasive,' requiring longer periods of rehabilitation. Families should be offered both procedures as part of comprehensive preoperative counseling.
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