Histochemical reaction to NPK fertilizer in the fascicular and reticular zones of the adrenal cortex

Male, white rats were kept for 30 days in an NPK fertilizer factory. The animals were then sacrificed and the samples of the fascicular and reticular zone of the adrenal gland were analyzed for fat substances. In the fascicular zone, as affected by NPK, the quantity of neutral lipids and triglycerides was decreased, whereas phospholipids were augmented. At the level of reticular zone the lowest rise in the quantity of neutral lipids was found, whereas the amount of the other two sorts of fat substances was conspicuously elevated. Nucleic acids change their presence in that pironynophilia disappeared; in the cells of both zones, the full discharge of RNA took place. Judging by the results obtained, the cells of both fascicular and reticular zone are in the phase of an intensified secretion.