LC-MS method 4 Determination of aniline derivative type specific migration of

The present invention provides a liquid mass Spectrometry four kinds of aniline derivatives of the specific migration method, said aniline derivative having a specific type 4 derived from plastic food packaging materials and containers, respectively, m-xylylenediamine , N- (4- hydroxyphenyl) acetamide, 4,4-diaminodiphenyl sulfone and 1,3-diphenyl-2-thiourea. The present invention, by high performance liquid chromatography - tandem mass spectrometry can be efficiently between simple and rapid simultaneous determination xylylenediamine, N- (4- hydroxyphenyl) acetamide, 4,4-diaminodiphenyl sulfone and 1 , 3-phenyl-2-thiourea aniline derivative 4 type specific migration, a good linear relationship and chromatographic separation, recovery and high accuracy, fully meet the requirements of the EU legislation limits. The present invention relates to a method of rational, sensitive, accurate, fast, simple features solve the problem of the specific migration aniline derivatives 4 type plastic food packaging materials and containers of harmful detected.