Epidémiologie hospitalière des patients co-infectés par le VIH et le VHC

Abstract Hospital epidemiology of patients co-infected by HIV and HCV. Objective To describe the epidemiology and the hospital management of patients co-infected by HIV and HCV. Method A “one-day” survey in 46 French hospitals. Results Among the 990 HIV positive patients, 95% were investigatyed for HCV and 33% of them were positive, 40% with a normal ALT level. The HCV-RNA serum level, obtained in 68%, was positive in 90%. Drinkers were 29%. 46% of the patients with RNA-HCV positive, had had a liver biopsy: 17% had moderate hepatitis, 68% severe hepatitis, 15% cirrhosis, 49% had been treated. The proportion treated was not different, according the ALT level; but more treated patients were found (p > 1%) among non-drinkers (58%) than among drinkers (20%). Furthermore, only 56% with severe hepatitis and 67% with cirrhosis had been treated. Comments This survey showed that a large proportion of HIV positive patients were also infected by HCV and are insufficiently investigated and treated.