Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae

SCV was supported by American Leprosy Missions Grant (G88726), MJS was supported by a grant from Foundation Botnar working to support children with cystic fibrosis (Project 6063), CHMR and SP were supported by Australian Government Research Training Program Scholarships, DBA was funded by a Newton Fund RCUK-CONFAP Grant awarded by The Medical Research Council and Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (MR/M026302/1) and by the Wellcome Trust Programme Grant (200814/Z/16/Z) and supported in part by the Victorian Government's OIS Program. TLB was supported by the Wellcome Trust Programme Grant (200814/Z/16/Z) and SM was supported by the MRC DBT Grant (RG78439).