Влияние топических фторхинолонов III поколения с консервантом и IV поколения без консерванта на эндотелий роговицы человека

Thirty nine patients (55 eyes) was inspected. Patients were divided into 2 groups. All patients preparing for cataract phacoemulsification and as a preoperative preparation received instillation of 0.5% moxifloxacin (for 1group of patients) and 0.5% levofloxacin (for 2 groups of patients). Endothelioskopy performed in the day of the first patient visit in the clinic and again immediately before surgery. In patients younger than 70 years the instillation of 0.5% moxifloxacin and 0.5% levofloxacin changes in morphological parameters of the corneal endothelium was equivalent, and not statistically significant for both groups, which speaks about the safety of medicines for patients of this group. Detected statistically significant changes in morphological parameters of the corneal endothelium in patients over age group, after applying the 0.5% levofloxacin. The discovery of circumstances should be considered in choosing antibacterial drugs for prevention of endophthalmitis preoperative and postoperative care, giving priority to effective antimicrobial drugs with minimal risk of injury to patients older than 70 years.