120: Changes in Sedation in the ICU due to COVID-19: A Multicentric Questionnaire

INTRODUCTION: A dynamic, multimodal and specific sedation and analgesia impacts gross outcomes such as mortality, morbidity and ICU stay while diminishing costs to the Health System Amid the COVID-19 pandemic, sedation and analgesia have increased To better manage said resources, its necessary to review how current practices differ from before the pandemic METHODS: To determine how sedation practices in the ICU have changed during the COVID-19 pandemic, a questionnaire designed by the investigation team was sent to 122 hospitals (78 colombian and 44 foreign) to collect data It consisted of 10 items Items 1-8 used a Likert scale to compare the frequency of usage of midazolam, propofol, physical restraints and dexmedetomidine when doing deep sedation (DS) before and during the COVID-19 pandemic Item 9 was about the average time COVID-19 patients were under DS and item 10 asked about the perception of delirium prevalence in the ICU during the pandemic The results were analyzed using SPSS v25 RESULTS: Seventy-nine questionnaires (64 8%) were answered, 64 (82,1%) were Colombian and 15 (34,1%) were foreign Midazolam for DS, before and during the pandemic respectively: Always (9,2% vs 19,7%), Frequently (25% vs 46,1%), Sometimes (55,3% vs 28,9%) and Never (10,5% vs 5,3%) Propofol for DS, before and during the pandemic respectively: Always (15,8% vs 11,8%), Frequently (50% vs 35,5%), Sometimes (32 9% vs 43,4%) and Never (1,3% vs 9,2%) Physical restraints for DS, before and during the pandemic respectively: Always (5,2% vs 23,7%), Frequently (23,7% vs 31,6%), Sometimes (64 5% vs 34,2%) and Never (6,6% vs 10,5%) Dexmedetomidine for DS, before and during the pandemic respectively: Always (18,4% vs 5,3%), Frequently (42,1% vs 31,6%), Sometime (26,3% vs 47,4%) and Never (13,2% vs 15,8%) Also, COVID-19 patients were under DS between 48 hours-5 days (54,4%), followed by 5-10 days (31,6%), >10 days (11,4%) and 85% of patients and 60,5% specialists perceive an increase in delirium prevalence