Evaluation of TOP2A and TIMP-1 as predictive markers of pathologic complete response to neoadjuvant anthracycline-based chemotherapy.

Joyce Maria L. Maia,Elizabeth Santana dos Santos,Rafael Costa Lessa,Felipe D'Almeida Costa,Stephania M. Bezerra,Rafael Malagoli Rocha,Carlos Frederico Lopes Benevides,Vladmir Cláudio Cordeiro de Lima,Adriana Regina G. Ribeiro,Marcello Ferretti Fanelli,Alexandre Andre Balieiro Anastacio da Costa,Celso Abdon Lopes de Mello

Evaluation of TOP2A and TIMP-1 as predictive markers of pathologic complete response to neoadjuvant anthracycline-based chemotherapy.

2013

Joyce Maria L. Maia
Elizabeth Santana dos Santos
Rafael Costa Lessa
Felipe D'Almeida Costa
Stephania M. Bezerra
Rafael Malagoli Rocha
Carlos Frederico Lopes Benevides
Vladmir Cláudio Cordeiro de Lima
Adriana Regina G. Ribeiro
Marcello Ferretti Fanelli
Alexandre Andre Balieiro Anastacio da Costa
Celso Abdon Lopes de Mello

e11503 Background: Factors predictive of response to anthracyclines can help selecting patients who really benefit from its use. HER2 amplification, TOP2A aberrations, and changes in tissue inhibit...

Keywords:

Oncology
Anthracycline
Internal medicine
Chemotherapy
Medicine
Pathology
HER2 Amplification
complete response

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