Ruthenium-Catalyzed Benzimidazoisoquinoline Synthesis via Oxidative Coupling of 2-Arylbenzimidazoles with Alkynes.
2013
Abstract Synthesis of a fused bis-heterocyclic framework, benzimidazoisoquinoline, has been achieved using Ru-catalyzed reaction of alkynes with 2-aryl benzimidazoles in the presence of Cu salts. The method provides an easy access for the generation of a library of benzimidazoisoquinoline derivatives.
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