Aggressive B-cell lymphoma involving the appendix and bilateral ovaries in an 11-year-old girl.
2020
Abstract Background The appendix and ovaries are rarely involved simultaneously in malignancies. The decision to perform ovarian biopsy or surgical resection in young patients can be challenging without sufficient clinical information. Case We describe an 11-year-old girl with bilateral ovarian masses, an enlarged appendix, associated pleural effusion and ascites. Appendectomy and biopsy of the bilateral ovarian masses lead to a diagnosis of aggressive B-cell non-Hodgkin’s lymphoma. The patient was treated with chemotherapy, which achieved complete remission and bilateral ovarian preservation. Summary and conclusion If ovarian involvement in malignant lymphoma is suspected, diagnostic methods should spare the ovary and prevent a loss of fertility. To evaluate for possible chemotherapy-induced ovarian damage, including infertility and premature menopause, an interdisciplinary approach is needed for the long-term follow-up of adolescent girls.
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