Effects of the cimaterol (CL 263,780) on growth and cellular metabolisms in the mammary gland of rats

Abstract This study was conducted to examine the effects of cimaterol feeding on growth performances and mammary growth and differentiation. Attempts were also made to investigate the cellular metabolisms of protein and fat in the mammary gland at the various physiological stages (virgin, pregnancy, early lactation, and late lactation). Ninety-six female Sprague Dawley rats (approximately 52.3 g) were randomly assigned to three treatments: CON (feeding the diet without cimaterol), CIM I (feeding the diet with cimaterol [10 mg/kg] from weanling to parturition), CIM II (feeding the diet with cimaterol from breeding to parturition). Cimaterol improved ( P P P