Novel chiral diamidophosphites for asymmetric metal-catalyzed reactions

AbstractChiral diamidophosphites with 1,3,2-diazaphospholidine cycles were prepared. A study of these chiral inducers showed them to provide up to 97% ee in the Pd-catalyzed allylic alkylation of (E)-1,3-diphenylallyl acetate with dimethyl malonate.