The influence of ipratropium bromide in the recovery phase of methacholine induced-bronchospasm.

Abstract The protective effect of Ipratropium Bromide (IB) in the methacholine-induced bronchospasm is well known from some time. The objective of the present study was to assess whether a pretreatment with IB may influence the subsequent phase of methacholine-induced bronchospasm relief. Sixteen patients with bronchial hyper-reactivity (PD20 FEV1