Pre- and post-contrast T1 mapping for detection of myocardial fibrosis in severe aortic stenosis before and after aortic valve replacement

Background Severe aortic stenosis (AS) leads to diffuse fibrosis in the myocardium, which could cause poor clinical outcome. Cardiovascular Magnetic Resonance (CMR) with recently T1 mapping is a promising technique to identify diffuse myocardial fibrosis. The Objective of the present study was to assess myocardial fibrosis by CMR using T1 mapping in patients with surgical AS and evaluate the evolution after aortic valve replacement (AVR). Methods