Urotensin II Induces ER Stress and EMT and Increase Extracellular Matrix Production in Renal Tubular Epithelial Cell in Early Diabetic Mice

Xin-Xin Pang,Qiong Bai,Fei Wu,Guan-Jong Chen,Ai Hua Zhang,Chao-Shu Tang

Urotensin II Induces ER Stress and EMT and Increase Extracellular Matrix Production in Renal Tubular Epithelial Cell in Early Diabetic Mice

2016

Xin-Xin Pang
Qiong Bai
Fei Wu
Guan-Jong Chen
Ai Hua Zhang
Chao-Shu Tang

Background/Aims: Urotensin II (UII) and its receptor are highly expressed in the kidney tissue of patients with diabetic nephropathy (DN). The aim of this study i

Keywords:

Endocrinology
Diabetic nephropathy
Urotensin-II
Extracellular matrix
Epithelial–mesenchymal transition
Internal medicine
Urotensins
Kidney
Diabetes mellitus
Receptor
Medicine
Epithelium

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