Parietal ganglioglioma. Apropos of a clinical case
2009
Ganglioglioma is not a frequent neuronoglial tumor, representing 1% of
all adult, and approximately 4% of the infantile primary brain tumors.
The more frequent symptom being convulsions, followed by signs of
intracranial hypertension. Although most are of a benign histological
type, some gangliogliomas are malignant de novo, and some undergo
malignant degeneration. They can arise at any location, most are
supratentorial, and the temporal lobe is the most frequent site of
occurrence, followed by the frontal and the parietal lobes. We present
the case of a female patient, 16-years old, who complained of headache
of approximately 6 months of evolution, accompanied by convulsions of a
simple partial type during the last months, with no other
symptomatology or other findings on physical examination, for this
reason imaging studies were indicated. On Magnetic Resonance imaging,
an image of cystic aspect was identified in the left parietal lobe,
with presence of a mural nodule towards the superior and external wall
of the lesion. H1 magnetic resonance spectroscopy was performed on
which choline elevation was observed being above the NAA and creatine
levels, likewise lactate and lipids were also increased. Pathology and
immunohistochemical studies reported ganglioglioma.
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