Parietal ganglioglioma. Apropos of a clinical case

2009 
Ganglioglioma is not a frequent neuronoglial tumor, representing 1% of all adult, and approximately 4% of the infantile primary brain tumors. The more frequent symptom being convulsions, followed by signs of intracranial hypertension. Although most are of a benign histological type, some gangliogliomas are malignant de novo, and some undergo malignant degeneration. They can arise at any location, most are supratentorial, and the temporal lobe is the most frequent site of occurrence, followed by the frontal and the parietal lobes. We present the case of a female patient, 16-years old, who complained of headache of approximately 6 months of evolution, accompanied by convulsions of a simple partial type during the last months, with no other symptomatology or other findings on physical examination, for this reason imaging studies were indicated. On Magnetic Resonance imaging, an image of cystic aspect was identified in the left parietal lobe, with presence of a mural nodule towards the superior and external wall of the lesion. H1 magnetic resonance spectroscopy was performed on which choline elevation was observed being above the NAA and creatine levels, likewise lactate and lipids were also increased. Pathology and immunohistochemical studies reported ganglioglioma.
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