An Evaluation of Two Different Schedules of Synthetic Thymosin α1 Administration in Patients with Lung Cancer

Thymosin α1 (molecular weight 3108) is one of the many active polypeptides isolated from thymosin fraction 5 (TF5) (Low and Goldstein, 1979; Goldstein et al., 1982). α1 was initially purified from extracts of calf thymus glands. Biologically active α1 has now been successfully synthesized by classical solution (Birr and Stollenwerk, 1979; Wang et al., 1978), solid-phase (Wang et al., 1980; Folkers, et al., 1980) and recombinant DNA procedures (Wetzel et al., 1980).