Development of personalized approach to the reconstruction of bone tissue defects using porous ceramic osteoimplants

A fundamentally new complex technique for preoperative planning and creation of individual implants from ceramics for the reconstruction of the maxillofacial region is clinically applicable and in demand in modern trends of reconstructive surgery were developed and approved. The developed method implies using of alumina based ceramic material, which meets the requirements for medical materials used in reconstructive surgery. It was shown that by varying the initial composition of the ceramic powder material, it is possible to achieve structural and mechanical affinity with the surrounding bone tissue. Building a 3D model of an osteoimplant on the basis of a computed tomography of the patient avoids the need for additional resection of the bone tissue and ensures complete geometric conformity of the osteoimplant to the prosthetic area. The method was approved by the reconstruction of the patient's skull-orbital complex using a three-dimensional personalized ceramic implant. The complete absence of the inflammatory reaction after surgery was observed.