Generation of a high-affinity Fcγ receptor by Ig-domain swapping between human CD64A and CD16A

Jeff L.Ellsworth1,5, Nels Hamacher2, Brandon Harder1, Mark Maurer1, Thomas R.Bukowski2, Megan Lantry2, Claire Noriega2, Mark W.Rixon2, Brian Fox3, Ken Lewis2, Brent Meengs2, Emily Rollins4, Karlien Greeff4, Jeff Meyer4 and Carl Birks2 Department of Immunology, Department of Protein Biochemistry, Department of Biomolecular Informatics and Department of Bio-Process Development, ZymoGenetics, Inc., 1201 Eastlake Avenue East, Seattle, WA 98102, USA