Usefulness of bevantolol for chronic, stable angina pectoris

Abstract An objective assessment of the efficacy of bevantolol was performed in 21 patients with chronic, stable angina using computer-assisted exercise testing and ambulatory ST-segment monitoring. Given once daily, 200 mg of bevantolol was compared with 200 mg of bevantolol given twice daily and with placebo, using a double-blind crossover technique. The mean exercise time with placebo was 7.4 ± 0.6 minutes; this increased to 10.6 ± 0.9 minutes (p −1 with placebo to 0.2 ± 0.03 mm min −1 (p −1 (p The mean number of episodes of ST depression over 24 hours in lead CM 5 was decreased from 6.89 ± 1.7 with placebo to 2.50 ± 0.6 (p