Binding of Aluminium(III)-Citrate Complexes, [Al3(H-1Cit)3(OH)]-4 and [Al3(H-1Cit)3(OH)4]-7, to Alzheimer's A-beta(1-40) Peptides : In situ Atomic Force, Electron Microscopy and Solid State 13C and 27Al NMR Studies

Oleg N. Antzutkin,Nils Norlin,Magnus Hellberg,P Eriksson,Nils Almqvist,Richard D. Leapman,Robert Tycko,Aneta T. Petkova,I. Tóth,A. P. Howes,Ray Dupree

Binding of Aluminium(III)-Citrate Complexes, [Al3(H-1Cit)3(OH)]-4 and [Al3(H-1Cit)3(OH)4]-7, to Alzheimer's A-beta(1-40) Peptides : In situ Atomic Force, Electron Microscopy and Solid State 13C and 27Al NMR Studies

2005

Oleg N. Antzutkin
Nils Norlin
Magnus Hellberg
P Eriksson
Nils Almqvist
Richard D. Leapman
Robert Tycko
Aneta T. Petkova
I. Tóth
A. P. Howes
Ray Dupree

It is believed that Alzheimer's disease (AD) amyloid-β-peptide (Aβ) deposits contribute directly to the disease's progressive neurodegeneration. Aggregation cascade for Aβ peptides, its relevance t ...

Keywords:

Crystallography
Solid-state
Progressive neurodegeneration
Beta-1 adrenergic receptor
Aluminium
Electron microscope
Chemistry
In situ

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