Pattern of Ipsilateral Breast Tumor Recurrence After Breast-Conserving Therapy

The rate of ipsilateral breast tumor recurrence (IBTR) in breast cancer after breast-conserving therapy was analyzed. We demonstrate that after 12 years' follow-up, there is an especially high recurrence rate for women ≤40 years old. For women ≤40 years old, the absence of adjuvant systemic therapy and the presence of lymph vascular space invasion (LVSI) are associated with a higher rate of IBTR. For women >40 years old, the presence of LVSI and lobular carcinoma in situ are prognostic factors for IBTR.