Novel heteroarene anthracenedione-based g-quadruplex ligands inhibiting tumour cell growth

FIELD: chemistry. SUBSTANCE: invention relates to linear heterocyclic anthracenedione derivatives containing guanidino(alkylamino) groups in positions 2, 4 and 11 and having the formula: as well as pharmacologically acceptable salts, where X independently denotes a heteroatom selected from O, S or an NH group which forms a five-member heteroarene condensed with an anthracenedione nucleus at bonds 2-3; n independently denotes a number from 2 to 4, which is equal to the number of spacer CH 2 groups which link amino groups in peri-positions of heteroarene anthracenedione with nitrogen atoms of guanidine group residues located in side chains; m independently denotes a number from 2 to 4, which is equal to the number of spacer CH 2 groups which link the nitrogen atom of a carboxamide group located at position 2 of the heterocyclic nucleus of heteroarene anthracenedione with the nitrogen atom of the guanidine group residue located in the side chain. EFFECT: obtaining novel compounds which can be used in medicine for therapy of cancerous diseases. 2 tbl, 2 dwg, 8 ex