Immunogenic peptides and their use

The invention relates to a method of screening in vitro to immunogenic peptides of interest can recognize antibodies from the serum of individuals with active tuberculosis, said method comprising: - serum peptides contacting derived from patients active TB - detecting the formation of immune complexes in the previous step, and - the selection of peptides of interest for which the value of a ratio R is greater than or equal to 1.5, the ratio R being the value measuring the immune complex formation on the measurement value obtained from the control sample.