Effectiveness and safety of 3 and 5 day courses of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

Kyaw Myo Tun,Atthanee Jeeyapant,Aung Hpone Myint,Zwe Thiha Kyaw,Mehul Dhorda,Mavuto Mukaka,Phaik Yeong Cheah,Mallika Imwong,Thaung Hlaing,Thar Htun Kyaw,Elizabeth A. Ashley,Arjen M. Dondorp,Nicholas J. White,Nicholas P. J. Day,Frank Smithuis

Effectiveness and safety of 3 and 5 day courses of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

2018

Kyaw Myo Tun
Atthanee Jeeyapant
Aung Hpone Myint
Zwe Thiha Kyaw
Mehul Dhorda
Mavuto Mukaka
Phaik Yeong Cheah
Mallika Imwong
Thaung Hlaing
Thar Htun Kyaw
Elizabeth A. Ashley
Arjen M. Dondorp
Nicholas J. White
Nicholas P. J. Day
Frank Smithuis

Background Artemisinin resistance in Plasmodium falciparum has emerged and spread in Southeast Asia. In areas where resistance is established longer courses of artemisinin-based combination therapy have improved cure rates.

Keywords:

Immunology
Biology
Pharmacology
Artemether/lumefantrine
Malaria
Plasmodium falciparum
Artemisinin
Tropical medicine
Combination therapy
Internal medicine
Parasitology
Regimen
Virology

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