Plasma Insulin and C-peptide in Normal and Glucose Intolerant Males: the Role of Hepatic Insulin Uptake
2009
. Plasma immunoreactive insulin and C-peptide were measured in the basal and glucosestimulated state in middle-aged males. Normals were compared with individuals with mild to moderate glucose intolerance. The results demonstrate the value of C-peptide measurements in the assessment of “true” insulin secretion and suggest that a reduced hepatic insulin extraction is a feature of the glucose intolerant state.
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