Methylation-Based Age Estimation Model Construction and Its Effectiveness Evaluation.

2019 
题目: 基于甲基化的年龄推断模型构建与效能评估. 目的: 筛选与中国北方汉族男性个体年龄相关的DNA甲基化位点并构建年龄推断模型。. 方法: 筛选21个候选甲基化位点,使用EpiTYPER技术平台在476份汉族男性血液DNA中检测包含上述位点在内的21个扩增片段,共获得153个DNA甲基化位点数据。. CONCLUSIONS: The age estimation model on Han males in northern China constructed in this study can be used to estimate the age of victims and suspects and to narrow the scope of investigation, and therefore has practical application value. 结论: 本研究构建的中国北方汉族男性个体年龄的推断模型,可用于公安实战中受害者和嫌疑人的年龄推断,缩小案件的侦查范围,具有实际应用价值。. 关键词: 法医遗传学;法医人类学;DNA甲基化;年龄测定;线性模型;汉族;中国北方;男性.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    0
    References
    0
    Citations
    NaN
    KQI
    []