Tumor volume is an independent predictor of survival in patients with malignant pleural mesothelioma

Tumor histology and stage are predictors of survival in patients with malignant pleural mesothelioma (MPM). The TNM classification that is widely accepted for MPM has its limitations. Significance of tumor volume, a better representation of tumor burden is not routinely determined. We hypothesized tumor volume is a better predictor of survival and complimentary to T and N stage. Extended pleurectomy and decortication (EPD), a lung sparing procedure, provides an opportunity to measure the tumor volume and pathological stage.