Spontaneous clearance of psoriasis during the course of Kikuchi-Fujimoto disease

Abstract A 23-year-old woman had psoriasis vulgaris since childhood. She noted painless enlargement of several lymph nodes in the cervical region accompanied by fever and malaise. A biopsy specimen from a cervical lymph node revealed histiocytic necrotizing lymphadenitis without granulocyte infiltration (Kikuchi-Fujimoto disease), a rare and benign lymphadenopathy of unknown cause. During the course of the Kikuchi-Fujimoto disease, the patient's recalcitrant psoriatic lesions spontaneously subsided. Complete clearance of psoriatic lesions continued until remission of Kikuchi-Fujimoto disease. (J Am Acad Dermatol 2002;47:S287-8.)